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Dr. Mack is an Associate Professor of Neurosurgery and a faculty member of the Neuroscience Graduate Program at University of Southern California. His area of clinical focus is endovascular and surgical management of patients with cerebrovascular disease.

Dr. Mack attended Columbia University, College of Physicians and Surgeons, where he graduated from medical school and completed Neurosurgical residency training. During residency, he performed a post-doctoral cerebrovascular research fellowship. Following residency, Dr. Mack completed an Interventional Neuroradiology/ Neuroendovascular Surgery fellowship at UCLA.

Dr. Mack is the Principal Investigator and Director of the Cerebrovascular Laboratory in the Zilkha Neurogenetic Institute. His overarching academic goal is to examine the effects of inflammation in experimental models of cerebrovascular disease. The group employs models of stroke and chronic cerebral hypoperfusion to assess environmental exposures and evaluate novel therapeutic agents. Current studies focus on the impact of inflammation and oxidative stress on the blood-brain barrier. 

Institutions: 
University of Southern California